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407.895.3300 | Vicki Brooks, Board of Commissioners Chair | Vivian Bryant, Esq., President/CEO
06/30/2025

Prescription Opioids: What You Need to Know

A hand holding a glass bottle prescription opioids.

Prescription opioids can be used to help relieve moderate-to-severe pain and are often prescribed following a surgery or injury, or for certain health conditions. These medications can be an important part of treatment, but they also come with serious risks. It is important to work with your health care provider to make sure you are getting the safest, most effective care.

What are the risks and side effects of opioid use?

Prescription opioids carry serious risks of addiction and overdose, especially with prolonged use. An opioid overdose, often marked by slowed breathing, can cause sudden death. The use of prescription opioids can have a number of side effects as well, even when taken as directed:

  • Tolerance - meaning you might need to take more of a medication for the same pain relief
  • Physical dependence - meaning you have symptoms of withdrawal when a medication is stopped
  • Increased sensitivity to pain
  • Constipation
  • Nausea, vomiting, and dry mouth
  • Sleepiness and dizziness
  • Confusion
  • Depression
  • Low levels of testosterone that can result in lower sex drive, energy, and strength
  • Itching and sweating

As many as 1 in 4 people* receiving prescription opioids long-term in a primary care setting struggle with addiction.
*Findings from one study

Risks are greater with:

  • History of drug misuse, substance use disorder, or overdose
  • Mental health conditions (such as depression or anxiety)
  • Sleep apnea
  • Older age (65 years or older)
  • Pregnancy

Avoid alcohol while taking prescription opioids. Also, unless specifically advised by your health care provider, medications to avoid include:

  • Benzodiazepines (such as Xanax or Valium)
  • Muscle relaxants (such as Soma or Flexeril)
  • Hypnotics (such as Ambien or Lunesta)
  • Other prescription opioids

Know Your Options

Talk to your health care provider about ways to manage your pain that don't involve prescription opioids. Some of these options may actually work better and have fewer risks and side effects. Options may include:

  • Pain relievers such as acetaminophen, ibuprofen, and naproxen
  • Some medications that are also used for depression or seizures
  • Physical therapy and exercise
  • Cognitive-behavioral therapy, a psychological, goal-directed approach, in which patients learn how to modify physical, behavioral, and emotional triggers of pain and stress.

If you are prescribed opioids for pain:

Be Informed!

Make sure you know the name of your medication, how much and how often to take it, and its potential risks and side effects.